Only the hardiest of runners will complete this circumnavigation of Pine Creek. A Pennsylvania scenic river carving its way through the rugged heart of the Appalachians. The largest creek in the United States that supplied the lumber that built America. The Iroquois called it Tiadaghton – the River of Pines. Or is it the Lost and Bewildered River? After traveling some of the most scenic and challenging trails in Pennsylvania, along with climbing more than 20,000 feet in the process, you may find that name more appropriate.